Buy Raloxifene Hydrochloride (Raloxifene HCL) Powder

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Raloxifene Hydrochloride

Product Name:   Raloxifene Hydrochloride Powder

CAS #:   82640-04-8

Purity:   99%

Raloxifene Hydrochloride Price:   According to your needs

Raloxifene Hydrochloride Half Life:  27 hours

Raloxifene Hydrochloride Dosage:   60 mg orally per day

Raloxifene Hydrochloride Detection time:   Currently unknown

Raloxifene Hydrochloride Side Effect:   Coughing blood;headache or migraine headache;loss of or change in speech, coordination, or vision;pain or numbness in chest, arm, or leg shortness of breath

Raloxifene Hydrochloride Results:   For treatment or prevention of osteoporosis, advise patients to add supplemental calcium and/or vitamin D if daily intake is inadequate;When this drug is used to reduce the risk of invasive breast cancer, the optimum duration of treatment is not known.

Raloxifene Hydrochloride Specifications:

COA

ITEMS SPECIFICATION RESULT
Characters
Appearance White &off-white powder Conform
Solubility Soluble in 10% sodium hydroxide solution. Slightly Soluble in methanol. Insoluble in water Conform
Identifications Infrared Absorption Conform
Chloride Conform
Tests Loss on drying ≤0.5% 0.4%
Residue on ignition ≤0.1% 0.06%
Heavy metals ≤10ppm Conform
RRelated substances Raloxifene Impurity1 ≤0.20 % 0.10%
Any unspecified individual impurity 2 ≤0.10% Max. 0.08%
Total impurities ≤0.50% 0.40%
Assay Raloxifene HCl ≥98.0% 99.0%

Raloxifene Hydrochloride Descriptions:

EVISTA (raloxifene hydrochloride) is an estrogen agonist/antagonist, commonly referred to as a selective estrogen receptor modulator (SERM) that belongs to the benzothiophene class of compounds.
The chemical designation is methanone, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl]-[4-[2-(1- piperidinyl)ethoxy]phenyl]-, hydrochloride. Raloxifene hydrochloride (HCl) has the empirical formula C28H27NO4S•HCl, which corresponds to a molecular weight of 510.05. Raloxifene HCl is an offwhite to pale-yellow solid that is very slightly soluble in water.
EVISTA is supplied in a tablet dosage form for oral administration. Each EVISTA tablet contains 60 mg of raloxifene HCl, which is the molar equivalent of 55.71 mg of free base. Inactive ingredients include anhydrous lactose, carnauba wax, crospovidone, FD&C Blue No. 2 aluminum lake, hypromellose, lactose monohydrate, magnesium stearate, modified pharmaceutical glaze, polyethylene glycol, polysorbate 80, povidone, propylene glycol, and titanium dioxide.

Raloxifene Hydrochloride Effects:

-Treatment and prevention of osteoporosis in postmenopausal women.
-Reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and/or at high risk of invasive breast cancer.

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Buy Testolactone (Teslac) Raw Powder

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Testolactone

Product Name:   Testolactone Powder

CAS #:   968-93-4

Purity:   ≥99%

Testolactone Price:   According to your needs

Testolactone Half Life:   Around 24 hours

Testolactone dosage:   (Oral) 250 mg three times per day

Testolactone Detection time:   Unknown

Testolactone Side Effect:   Abnormal skin sensations;Aches of the legs and arms;General body discomfort;Hair loss;Loss of appetite;Nausea;Redness of the tongue;Vomiting

Testolactone Results:   Treating various types of breast cancer in women;blocking the production of estrogen;prevent tumor cells from being activated by other hormones;postpone precocious puberty because of its ability to block estrogen production.

Testolactone Specifications:

COA

TEST ITEMS SPECIFICATION RESULTS
Description : White or Almost White Crystalline Powder white powder
Identification : A.B. Positive
Assay : 97.0~102.0% 99.3%
Specific Rotation : +101°~+105° +102.6°
Loss On Drying : 1.0%max 0.27%
Melting Point : 153~157°C 153.0~155.0°C
Organic Volatile Impurities : meets the requirement. Conforms
Related Substances : meets the requirement. Conforms
Residual Solvents : meets the requirement. Conforms
Particle Size : 100% ≤ 20 microns Conforms
Conclusion The specification conform with USP30 standard

Testolactone Descriptions:

Testolactone is an antineoplastic agent, prescribed for breast cancer in postmenopausal women. It works by blocking the production of estrogen.

Testolactone Effects:

Testolactone is mainly used for treating various types of breast cancer in women who have been through menopause or whose ovaries no longer function. It works by blocking the production of estrogen, which helps prevent the growth of breast cancers that are activated by estrogen. It may also prevent tumor cells from being activated by other hormones. It also has been used to postpone precocious puberty because of its ability to block estrogen production.

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Toremifene citrate

Product Name:   Toremifene Citrate Powder

CAS #:   89778-27-8

Purity:   99%

Toremifene Citrate Price:   According to your needs

Toremifene Citrate Half Life:   Around 5 days

Toremifene Citrate dosage:   For bodybuilding purposes, a dose of 40-60mgs per day seems to be a good starting point. If the user is trying to fight existing gynecomastia (bitch tits), they may choose to double the dose and add an aromatase inhibitor like Aromasin with it. For PCT, some users will kick-start with 100-120mgs per day and then lower to 40-60mgs per day for 4-6 weeks.

Toremifene Citrate Detection Time:   Unknown

Toremifene Citrate Side Effect:   Sweating;Nausea;Mood swings;Vision problems;Dry eyes;Swelling of legs and hands;Rash

Toremifene Citrate Results:   Weight loss and muscle growth for bodybuilder and athletes

Toremifene Citrate Specifications:

COA

Description White or Almost White Crystalline Powder white powder
Identification A.B. Positive
Assay 97.0~103.0% 99.0%
Specific Rotation +101°~+105° +102.6°
Loss On Drying 1.0%max 0.28%
Organic Volatile Impurities meets the requirement. Conforms
Related Substances meets the requirement. Conforms
Residual Solvents meets the requirement. Conforms
Particle Size 100% ≤ 20 microns Conforms

Toremifene Citrate Descriptions:

Fareston (Toremifene Citrate, known in bodybuilding circles as “torem”) is a selective estrogen receptor modulator (SERM) derived from triphenylethylene. It is FDA approved for breast cancer treatment, and has possible medical uses for prostate cancer. Bodybuilders will use this drug to combat gynecomastia (bitch tits), but it’s still very new to the scene and has some drawbacks.

Toremifene Citrate Effects:

Toremifene citrate is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body. Licensed in the United States under the brand name Fareston, toremifene citrate is FDA-approved for use in advanced (metastatic) breast cancer. It is also being evaluated for prevention of prostate cancer under the brand name Acapodene.
It has already been covered that Toremifene is a SERM, and serves to block Estrogen at various receptor sites in certain tissues within the body (breast tissue in particular). As a layman explanation, Toremifene pretends to be a ‘fake’ Estrogen that occupies Estrogen receptors within breast tissue. With these receptors occupied by Toremifene, real Estrogen cannot perform their jobs there. Toremifene does not reduce total blood plasma levels of Estrogen. In addition to being antagonistic to Estrogen receptors in breast tissue, it is also antagonistic to Estrogen at the hypothalamus gland (this essentially ‘tricks’ the hypothalamus into thinking there is little or no circulating Estrogen levels in the body, causing it to increase its manufacture of Testosterone so that it can utilize aromatization to restore these levels.
Toremifene is also agonistic to Estrogen receptors in other tissues in the body (within the liver in particular). This means that whileToremifene will act as an anti-estrogen in breast tissue and the hypothalamus, it will act as an Estrogen within the liver. This can have beneficial impacts especially during an anabolic steroid cycle, such as improving and shifting cholesterol levels into a more favorable range.

Buy Formestane (Lentaron) Raw Powder

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Formestane

Formestane Description:

Formestane (lentaron, chemical name: 4-hydroxyandrostenedione) is a type I steroidal aromatase inhibitor (AI). It was developed for use in treatment of estrogen-receptor-positive breast cancer in post-menopausal women. For medical purposes, it is made in intramuscular depot form and injected. It is not used in oral form due to poor bioavailability, which makes the oral version inferior to aromasin, letrozole, and arimidex.

Supplement companies, with a bodybuilder customer base, have made it in topical form. It was available as part of gel stacks, which are rubbed onto the skin with no need for injection. That allowed transdermal delivery, bypassing the liver. In case you are wondering, the reason I use “was” is because formestane is now illegal and a scheduled drug.

History and Ban

Formestane was derived from androstenedione, with the only difference being the addition of a 4-hydroxy group. From the late 2000′s until its ban in late 2014, it grew in popularity among bodybuilders. Its success came from the ability to easily use it in topical gel form.

On December 18, 2014, the Designer Steroid Anabolic Control Act of 2014 was signed into law, making formestane illegal. Since the signing of the act, it has disappeared from the supplemental market onto the black market.

Formestane and Cancer

Some cancers require estrogen to grow, and aromatase is an enzyme that synthesizes estrogen. Formestane is a 2nd generation aromatase inhibitor that blocks this synthesis. Thereby, it lowers estrogen levels and slows cancer growth in the breasts of women.

Bodybuilding

There are 2 main uses for formestane, which help bodybuilders who use anabolic-androgenic steroids (AAS).

Decreasing SHBG

According to studies, formestane can lower SHBG up to 34%, which will increase free testosterone levels. SHBG (sex hormone binding globulin) is a protein that binds to sex steroids, and renders them inactive, for as long as SHBG is bound to them. There is a difference between ‘free’ testosterone, and ‘bound’ testosterone. Free testosterone is what matters, so lowering SHBG will increase ‘free’ testosterone. Higher testosterone means more strength, muscle mass, less body fat, better sense of well being, and libido.

Aromatase Inhibitor

Many anabolic steroids aromatize in the body into estrogen. The most common are deca durabolin, equipoise, testosterone, and dbol. If an AI is not used, estrogen will increase and potentially cause major problems with estrogenic side effects. The most common side effects of estrogen are gynecomastia (bitch tits), excessive water retention (moon face), high blood pressure (hypertension), and insomnia.

In addition, coming off cycle with estrogen levels that are too high can hinder recovery of the body’s HPTA, causing gains on cycle to be lost. Formestane, while being used, will permanently disable the aromatase enzyme, so that it does not rebound after cycle. Other AI’s, such as letrozole and arimidex will not stop estrogen rebound.

Suicidal AIs vs Non-Suicidal AIs

There are two types of aromatase inhibitors.

Non-steroidal aromatase inhibitors such as arimidex, and the very potent letrozole, which inhibit the aromatase enzyme by reversible competition.

Suicidal (irreversible) steroidal aromatase inhibitors, such as aromasin, which will form a permanent bond with the aromatase enzyme that permanently deactivates it. The reason we call these suicide AI’s is because these compounds sacrifice their structural independence to disable the aromatase (estrogen) enzyme permanently.

Formestane falls into the 2nd category of suicide aromatase inhibitors, so no estrogen rebound should occur. After formestane use is discontinued, it will take time for aromatase to become active again.

Formestane Side Effects

Formestane does not cause many side effects unless abused. Sometimes bodybuilders will complain of dry joints, mood swings, libido changes, or rashes, which are typical of all AI’s. Another side effect is lower HDL (good) cholesterol, so you have to watch your diet.

Formestane Dosages

The most common version of formestane sold was in a topical gel form and it was dosed at 100-200mgs per application. Users would apply it onto clean, dry skin and rub in thoroughly; usually on the thighs or upper arms. It took 1 to 5 minutes to dry.

The injectable version for both breast cancer purposes and bodybuilders is 125mgs twice per week or 250mgs once per week.

Formestane Half Life

Formestane half life is about 4 days, which is in line with other aromatase inhibitors.

Buy Exemestane Aromasin Pure Raw Steroid Powder

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Exemestane

Aromasin is a steroidal AI which keeps it from negatively affecting your lipids like other non-steroidal AIs. It is also not liver toxic, and can be ran for longer lengths of time without negative effect. This makes it a better option to run on cycle from a pure health standpoint. Aromasin will not hurt your gains on cycle like other AIs, but may actually help them. Another benefit on cycle is that steroidal AIs lower SHBG which increases the ratio of free to bound testosterone. What that means during your cycle is a very positive impact on your gains. This (in a sense) makes your Anabolic Androgenic Steroids more bio-available.

The half-life of Aromasin is only about 9 hours, and clears quickly. However, because of how effective Exemestane is at eliminating Aromatase enzymes (80-90% after administration), estrogen levels will remain low up to 72 hours after a single dose of 25mg. This is why aromasin is very effectively dosed every other day. In one study, users were still 40% below baseline estrogen values 72 hours after their dose. This makes aromasin very versatile for dosing and not require more frequency.

Now, the place where Aromasin really shines is in post cycle therapy (PCT). There is simply no other Aromatase inhibitor that can compare in terms of its effects on recovery. We already mentioned how Aromasin lowers SHBG, which increases free testosterone.

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Buy Anastrozole Arimidex Pure Raw Steroid Powder

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Anastrozole Arimidex

When a man uses anabolic androgenic steroids (AAS), certain compounds will aromatize into estrogen. The main culprits that will do this are all testosterone esters, such as: cypionate, enanthate,dianabol, deca durabolin, and less so Boldenone (EQ). If estrogen isn’t inhibited by using an AI (aromatase inhibitor), then high-estrogen side effects can occur. The most well-known side effect is gynecomastia or what is known commonly as ‘gyno’, ‘bitch tits’ or ‘man breasts’. A man may notice a lump forming within his breast(s) – or under the nipple area; if not treated quickly, this can require serious surgery to remove. The lesser known but very serious side effects are caused by water retention, which can give a bloated or ‘full’ look. Extra water weight to your body or face (commonly called “moon face for its round or full look) can ruin a nice physique by making a person look fat. Internally, carrying around extra water weight will strain the body’s lipids across the board. A person can expect a rise in blood pressure, heart strain, and loss in energy. Also, high estrogen can affect libido.

On the other hand, if you are too aggressive in inhibiting estrogen, by using compounds that are harsher than Arimidex, this can cause your estrogen to drop too low. As a result, you can expect erectile disfunction (ED), loss of energy, depression and low libido.

Arimidex Dosage

Dosages of arimidex will vary from person to person. This is why blood work is essential to finding the perfect balance. One should start out at half a mg every other day and adjust as needed for the cycle. Some AAS users will not use an AI at first but they will have it on hand just in case. This isn’t always a good idea, as once you start noticing gyno or excessive water weight it could be too late to reverse. Since AAS will continue building in the body and aromatize (steroids turning into estrogen), taking arimidex at this point would be like trying to stop a car already in motion.

General dosages for men: 0.5mgs per day or every other day. Remember, it’s steroid dose dependent.

Arimidex Half-Life

The half-life of arimidex is around 46 hours, so it tends to build up in your system when used daily.

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Letrozole Powder

Letrozole (trade name Femara) is an oral aromatase inhibitor (AI) used in the treatment of hormonally responsive breast cancer after surgery. The FDA approved its use in post menopausal women who show hormone receptor positive types of breast cancer. It was banned in India in 2011 due to potential risk to infants when used in women who are pregnant; however, a Canadian study done by the American Society of Reproductive Medicine showed no evidence of birth defects. As a result, it remains legal in the rest of the world.

Letrozole Dosages

Letrozole Half Life

Dosages vary quite a bit, 0.25mg up to 1mg every day or every other day is a good starting dose. It’s best to be conservative with the dosage because if you overdose the sides can be harsh.

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Buy Mesterolone Proviron Pure Raw Steroid Powder

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Mesterolone

Proviron is popularized as an anti-estrogen because it is has a high affinity to bind to the aromatase enzyme, so anabolic steroid (AS) users could use it to serve as their AI (aromatase inhibitor) replacement. Bodybuilders were using it during post cycle therapy (PCT)

Another benefit of proviron is that it binds very well to SHBG (sex hormone binding globulin), which is the hormone responsible for reducing free testosterone circulating in the body. This is probably the reason why some use proviron during PCT.

Since it has no anabolic properties, proviron is worthless when used alone by a bodybuilder. However, when stacked, it can turn a wet compound into a perfect balance of size and hardness for your muscles,Proviron can be stacked with any anabolic steroid safely. In fact, it’s been called oral masteron by many, and rightfully so.

Dosages and Half Life

The half life of proviron is around 12 hours. A good recommended dosage is 25-75mg per day; The detection time is 5-6 weeks. so those that are tested often would be wise to avoid this compound. Females are not advised to take proviron because of its DHT properties. Side effects for females can be very nasty and unpredictable.

 

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Proviron is the brand name for the oral androgen Mesterolone (1 Methyl-Dihydrotestosterone). This steroid is a very strong androgen that doesn’t aromatize in estrogen. In clinical trials, Proviron was used for sexual dysfunction because it helped increase the testosterone levels. In most cases, the problem was reversed, allowing people to experience an interest in sex again as well as the ability to maintain an erection.
Proviron is a strong androgenic, but it is not strong enough to build muscles. This is because it is rapidly reduced to inactive metabolites in muscle tissue, a trait also characteristic of Dihydrotestosterone. This compound blocks androgen receptors in muscle tissues and it can reduce the gains made by other effective types of muscle building steroids.

Mesterolone / Proviron Dosages
Proviron is usually well tolerated and side effects are rare with dosages under 100 mg per day. Typical androgenic side effects include oily skin, acne, body/facial hair growth and exacerbation of a male pattern baldness condition, and may occur even with the use of a moderate dosage. With the strong effect DHT has on the reproductive system, androgenic actions may also include an extreme heightening of male libido.
Women should be careful around Proviron. It is an androgen, and as such has the potential to produce virilization symptoms quite readily. This includes, of course, a deepening of the voice, menstrual irregularities, changes in skin texture and clitoral enlargement.

Mesterolone / Proviron Side Effect
In women: risk of virilization effects, including deepening of the voice, menstrual irregularities, changes in skin texture and clitoral enlargement. In men:oily skin, acne, body or facial hair growth and exacerbation of a male pattern baldness condition, as well as several effects on the reproductive system like extreme heightening of male libido.

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Tamoxifen Citrate

Nolvadex is the trade name for the drug Tamoxifen Citrate,

Nolvadex works very similarly to clomid. It’s an antagonist of the estrogen receptors to-which it binds itself preventing active estrogen from binding in its place. Unlike AI’s such as aromasin, letrozole, orarimidex, which actually reduce the flow of estrogen in the body, nolvadex merely blocks estrogen from the receptor. This means there is a greater chance of an estrogen rebound effect.

When gyno prone anabolic steroid users run aromatising compounds, such as testosterone or dianabol, they convert to estrogen. This can lead to puffy nipples, bloating, blood pressure, erectile dysfunction (ED) and other estrogen related sides. Nolvadex can prevent some estrogen-related side effects from occurring, and it can halt the growth of gynecomastia. However, in my opinion, using an AI is much more effective for overall estrogen control.

In practice, tamoxifen is best used to help boost LH and total testosterone. This will help you recover from a cycle, which makes it a popular choice for post cycle therapy (PCT). A clomiphene, tamoxifen combination is one of the best recovery options for most PCT regiments.

Tamoxifen Citrate Dosage

You should start with 10-20mg every other day at the most, and see how the dosage works for you. Make sure to run it as a part of a complete post cycle therapy.

Tamoxifen Citrate Half-Life

Tamoxifen Citrate has a 6 day half-life, but in different medical documents it’s shown between 5 and 7 days.

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Clomifene Citrate Clomid Powder.jpg

Product name: clomifene dihydroen citrate

Another name:clomiphene citrate; CLOMEPHENE CITRATE; Clomifene Citrate; 2-(4-[2-Chloro-1,2-diphenylethenyl]phenoxy)-N,N-diethylethanamine citrate; 2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate (1:1); 2-{4-[(Z)-2-chloro-1,2-diphenylethenyl]phenoxy}-N,N-diethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate (salt); 2-{4-[(E)-2-chloro-1,2-diphenylethenyl]phenoxy}-N,N-diethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate (salt)

CAS: 50-41-9; 43054-45-1

EINECS: 200-035-3

Molecular formula: C32H36ClNO8

Molecular weight: 598.0831

InChI: InChI = 1 / C26H28ClNO.C6H8O7 / c1-3-28 (4-2) 19-20-29-24-17-15-22 (16-18-24) 25 (21-11-7-5- (11) 12) 2-4 (9) 10 / 9-12 (7) (H, 9,10) (H, 11,12) / b26-25 +; (H, 7,8)

Molecular structure: Clomiphene dihydro citrate 50-41-9; 43054-45-1

Boiling point: 509 ° C at 760 mmHg

Flash point: 261.6 ° C

Vapor pressure: 1.77E-10mmHg at 25 ° C

Assay:98%min

Package:1kg/foil bag

Appearance:white powder

Clomid, or Clomiphene Citrate, is a SERM (selective estrogen receptor modulator), so it’s in the same grouping as tamoxifen (nolvadex). It is the most widely prescribed drug for ovulation induction, which is useful for those who are infertile. Studies have shown a pregnancy rate of 5.6% per cycle with clomid treatment vs 1.3% without. This makes clomid an inexpensive and excellent fertility drug for females.

Male bodybuilders who cycle anabolic androgenic steroids (AAS) have found that the same mechanisms of increased LH (luteinizing hormone) can be taken advantage of to increase total testosterone levels. This is why clomid is popular in post cycle therapy (PCT) among those who cycle anabolic steroids. Since clomid has ability to bind to the estrogen receptors, much like nolvadex, in male users who run estrogenic compounds such as testosterone, dianabol, and deca durabolin, it can be used as gynecomastia treatment (anti-gyno). However, clomid is a fairly weak anti-gyno aid, and is rarely used for that purpose. Due to its ability to boost testosterone levels, it has been put on the WADA (world anti-doping agency) list of illegal doping agents in sport.

Clomifene Citrate Dosage

a dose of 50-100 mgs per day is enough to do the job. a 150mg per day dosage of clomiphene citrate can increase testosterone levels by 150%,when used at higher dosages, over 200mgs per day, side effects may include feeling depressed or ‘bitchy’; When used at a proper dose and when stacked with PCT aids such as: HCGenerate, Cardarine (GW) and N2Guard, the user will rarely have any side effects. Many users experience a spike in libido, ejaculation volume, and well being during this period when clomid is used properly, clomid is a great option for post cycle therapy. If used properly, users will report very little side effects and many benefits.

Clomifene Citrate Half-Life

Clomiphene Citrate half-life is around 5 to 7 days, so you can take an average 6 day half-life as a reference point.